10 Safe Ways To Biohack Your Brain: Supplements And Routines Relevant In 2017 And 2018


Watch the movie trailer below. It’s about a writer who changes his life around by taking a drug that unlocks 100% access to his brain abilities as to the normal 20.

Exciting isn’t it? I sure loved it when it first came out in 2011. But did you know that this movie is not entirely a fiction? Biohacking the brain for improved performance is real. There are world leaders, entrepreneurs and artists that have been doing this all along, and now you can do too. Here are 10 ways to biohack your brain for improved performance, health and longevity.

Please Note: Keep in mind that natural supplements aren’t always 100% safe, this is especially true if you take other medications. Talk to your doctor before adding any brain supplements and check for possible drug-interactions here.


#1 Nootropic Supplement

$21.04 $49.99

Nootropic supplements are legal supplements that improve the physical health of the brain, memory and clarity. Nootropics are a shotgun approach towards brain health as different brands concoct their supplements with varying ingredients known to boost brain function. Therefore some products may work for you while the others may not. Ideally, an effective nootropic supplement should contain separate ingredients for:

  • Tissue building and repair (amino acids for the brain)
  • The production or release of neurotransmitters (brain signals)
  • Brain stimulant for attention, clarity and focus
  • And, little to no filler ingredients.

Neuro-Peak is a natural nootropic supplement which currently ranks #75 in Amazon’s Best Sellers Rank (during research, I was personally fascinated about their ranking as most people are not aware of nootropic supplements). The supplement contains:

  • DMAE (Dimethylaminoethonal) to promote the production of acetylcholine (neurotransmitter),
  • PHOSPHATIDYLSERINE, for cell membrane structures, supporting memory and brain nerve cell health,
  • BACOPA MONNIERI, a natural chemical compound found in Bacopin (herb) to support memory function,
  • RHODIOLA ROSEA EXTRACT, a Russian herb to prevent brain fatigue and stress
  • GINKO BILOBA EXTRACT, herb extract for mental alertness, concentration and brain blood circulation,

Which essentially ticks all the boxes for it to be a highly-recommendable nootropic supplement. Nootropics are also known as smart drugs or cognitive enhancers and multiple studies have proven its effects (1,2). However, the use of such supplements by healthy individuals remain controversial and debated among scientists and health care practitioners for a number of issues, including ethics and fairness of their use. Nonetheless, nootropics are now a billion dollar industry and if this is your first time hearing about it, you may be missing out.


#2 Magnesium Threonate

Magnesium is an essential dietary mineral required in more than 300 enzyme systems including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. As important as it is, magnesium is the second most deficient nutrition in developed countries (3,4). Signs and symptoms due to magnesium deficiency include:

$29.95 $35.95
  • Lack of focus and clarity
  • Brain fog
  • Low tolerance to stress
  • Insomnia
  • Fatigue

Studies have shown that magnesium supplementation is effective in many mental disorders including depression, anxiety, ADHD, bipolar disorder and schizophrenia (5-8). There are many forms of magnesium supplements to choose from, but only magnesium l-threonate crosses the blood-brain barrier, thus making it the best for the purposes of brain supplementation (9). It’s unique ability to enter and increase magnesium concentrations in the brain makes it an excellent choice for improving:

  • Memory
  • Attention
  • Depression
  • Anxiety


Make sure to look for magnesium threonate supplements and NOT the inexpensive variants of magnesium such as oxide or sulfate as they yield very low bioavailability. The only reported side effects of magnesium threonate are headaches and drowsiness in the first week or so of use (10).



#3 Citicoline

$24.95 $29.95

Citicoline is a naturally occurring compound in the body. It was originally developed in Japan for stroke patients and was later introduced to European countries as a prescription drug for brain disorders. Today, citicoline is marketed as a brain supplement (11). Citicoline is still less widely known in today’s market but it’s one of the most effective ones. It’s known to:

  • Build healthy brain cell membranes
  • Improve blood flow to the brain
  • Improve brain plasticity
  • Increase brain energy by stimulating the mitochondria
  • Reduce harmful effects of free radical damage and inflammation (main causes of brain ageing)
  • Elevate levels of acetylcholine (neurotransmitter involved with memory and learning)

Some of the known side effects include insomnia, headache, diarrhoea, low or high blood pressure, blurred vision and chest pains (12).






#4 Vinpocetine

$19.99 $39.99

Vinpocetine is a new brain booster that blurs the line between brain supplement and smart drug. It’s based on vincamine, a chemical found in periwinkle (Vinca minor), a species of flowering plant native to central and southern Europe. In the medieval times, it was used to treat headaches, memory loss and vertigo (13). Vinpocetine is known to:

  • Improve memory
  • Fight brain fog
  • Improve mental clarity
  • Protect against brain ageing
  • Decrease brain inflammation
  • Improve the brain’s ability to use glucose (especially after a stroke)

In some parts of the world, vinpocetine is only available through prescription but is currently available in the U.S. as a brain supplement. The FDA is reviewing this and many speculate that vinpocetine will be made unavailable not because of safety concerns but because many believe that vinpocetine should be classified as a drug, not a health supplement (14).


#5 Exercise

This may come as a surprise as all the aforementioned brain-enhancers were in the forms of tablets, pill or herbs. Don’t take this lightly, exercise is probably one of the most effective and natural means of promoting brain health and mood regulator without the side-effects.

Numerous research shows that exercise improves cognitive function by the mechanism of increasing levels of brain-derived neurotrophic factor (NDNF). This protein is known to improve memory, learning and higher thinking by stimulating new growth of new neurones and maintaining existing neuronal pathways in the brain.

A 2010 study on primates in the Journal of Neuroscience also revealed that regular exercise not only improved brain blood circulation but also helped the monkeys learn new tasks twice as quickly as non-exercising monkeys. Many agree that this benefit is directly applicable to us humans.


#6 Turmeric

With over 9,000 studies under its belt, it is widely accepted that turmeric is the most potent herb known to man (I strongly recommend you to read this article for more information on turmeric. If you aren’t taking it daily, you are missing out). Curcumin is the main bioactive compound that makes turmeric so potent. Studies have revealed that turmeric can potentially prevent cancer, fight inflammation and even improve Alzheimer’s disease. Turmeric is also a potent brain booster with the following effects:

  • Increase levels of dopamine and serotonin (chemicals responsible for happiness in the brain)
  • Antidepressant effects that rival Prozac
  • Increase blood flow to the brain as effective as physical exercise
  • Improving memory and attention in elderly within an hour after taking a single dose (15)

The addition of piperine (black pepper) increases turmeric absorption by up to 2,000%. Turmeric has shown to cause diarrhoea and nausea, especially in high doses as side effects.


#7 Acetyl-L-Carnitine


Acetyl-l-carnitine (ALCAR) is an amino acid that increases both mental and physical energy (16). This compound is naturally found in red meat, seafood and dairy products, however these do not provide sufficient amounts of acetyl-l-carnitine to have any significant effects Red meat is the highest source of ALCAR at about 56-162mg per serving whereas the recommended dose ranges from 630 to 2,500mg per day and up to 4,000mg for Alzheimer’s (17,18). Therefore this compound is better taken as a supplement. ALCAR is known for its:

  • Powerful antioxidant properties, protecting the brain from free radical damage
  • Increase in neurotransmitters: serotonin and norepinephrine (antidepressant)
  • Improve mental clarity, focus, mood, processing speed and memory
  • Helpful for chronic fatigue syndrome (19), Alzheimer’s and Parkinson’s







#8 Lion’s Mane

Also known as a “Smart Mushroom”, Lion’s mane (Hericium erinaceus) is an edible mushroom found in parts of Asia, North America and Europe. The fungi have a long history of use in Traditional Chinese Medicine for the past 2,000 years. The most recent 2013 study concluded that: “this mushroom is rich in some physiologically important components, especially β-glucan polysaccharides, which are responsible for anti-cancer, immuno-modulating, hypolipidemic, antioxidant and neuroprotective activities of this mushroom (20).” It’s been said that lion’s mane can impart “nerves of steel” and the “memory of a lion”. The fungi has shown to:

  • Improve mental function: memory, intelligence, motivation, concentration
  • Improve a wide range of cognitive and neurological disorders (anxiety, depression, Alzheimer’s and Parkinson’s (21)
  • Produce NGF (Nerve Growth Factor) used for the growth and maintenance of neurones.


#9 Gut Flora

Your gut is filled with ‘good bacteria’ that become disturbed throughout life. A baby born through cesarian section misses out on the much-needed exposure to bacteria in the mother'’ womb and birth canal. We are exposed to an array toxins including pollution, antibacterial hand soap, processed foods, antibiotics and smoking, which leads to a state of gut bacteria deficiency. A recent study published by the Canadian Medical Association (2013) have linked the disruption of our normal gut flora (the good bacteria in your gut) with many inflammatory and immune-related diseases such as allergy, asthma and even cancer. The statistics are jaw-dropping:

  • A five-fold increased risk of allergies
  • Triple the risk of ADHD
  • Twice the risk of autism
  • An 80 percent increased risk of celiac diseases
  • A 50 percent increased risk of becoming obese (also linked with dementia)
  • A 70 percent increased risk of type-1 diabetes

The gut bacteria is also known as your “second brain” as the gut directly communicates with the brain via the vagus nerve (the 10th cranial nerve that runs from your brainstem into the enteric nervous system). A healthy gut flora prevents many brain disorders (as mentioned above) but also regulates mood, behaviour and brain health.

The best way to promote a healthy gut is by taking probiotics. Some of the best foods are kimchi and kefir, but if they’re not your thing, I strongly recommend probiotics. Read this article for more information on probiotics and its effects on the gut and your overall wellbeing.


#10 Chiropractic

And finally, Chiropractic. The brain and spine combine to form the central nervous system and it is a known fact that the spine directly impacts brain function. But how does chiropractic help? Here’s a quote from Dr Heidi Haavik, “We do know that spinal function does affect brain function. There’s now solid evidence that adjusting the spine changes brain function. This is the fourth time that the effect of adjusting the spine has on the brain has been studied. This last time it was studied and confirmed by an independent medical researcher.” Her research has been published in Neural Plasticity and found the following:

  • Chiropractic adjustments causes changes in the prefrontal cortex of the brain
  • Chiropractic adjustments improves sensorimotor function relevant in fall-prevention (Falls are the leading cause of injury-related visits to emergency departments in the U.S. 22)
  • Improved joint-position sense in upper and lower limb
  • Better ability to perform mental rotation of objects (Think problem-solving and clarity)

Chiropractic is not just for low back pain and headaches. They offer so much more (for example, chiropractic resets the brain and provides stress-relief) and the profession is quickly becoming more relevant as people continue to live a sedentary lifestyle on their computers and smartphones.


Biohacking your brain is not anymore a gimmick nor is it condemned. It’s a viable way of boosting brain capacity, function and health. There are many different ways you can achieve this, I personally prefer the natural route of combining regular chiropractic care, exercise, kefir/kimchi and turmeric, but I am considering to incorporate vinpocetine. Which option appeals to you? This list of ten different approaches/supplements are very relevant in our age today and you should definitely consider optimising your brain. Becoming a better version of yourself requires a lot more discipline and routines, a box of pills are never going to be enough. But that little edge over others may result in huge returns.



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  3. Magnesium Fact Sheets for Health Professionals https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/ available from National Institutes of Health
  4. https://www.ncbi.nlm.nih.gov/pubmed/25540137
  5. http://umm.edu/health/medical/altmed/supplement/magnesium
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738337/
  7. http://europepmc.org/abstract/med/9368236
  8. http://www.psychiatrictimes.com/bipolar-disorder/integrative-treatment-bipolar-disorder-review-evidence-and-recommendations/page/0/2
  9. https://www.sciencedaily.com/releases/2010/02/100222162011.htm
  10. http://magtein.com/consumer-faqs.html
  11. http://www.webmd.com/vitamins-supplements/ingredientmono-1090-citicoline.aspx?activeingredientid=1090
  12. http://www.rxlist.com/citicoline-page2/supplements.htm
  13. http://www.uofmhealth.org/health-library/hn-3659003
  14. http://www.nutraingredients-usa.com/Regulation/FDA-rules-vinpocetine-not-a-legal-dietary-ingredient-despite-successful-NDI-filings
  15. https://www.ncbi.nlm.nih.gov/pubmed/25277322
  16. https://www.ncbi.nlm.nih.gov/pubmed/22549035
  17. http://www.webmd.com/vitamins-supplements/ingredientmono-834-acetyl-l-carnitine.aspx?activeingredientid=834&activeingredientname=acetyl-l-carnitine
  18. https://examine.com/supplements/L-Carnitine/
  19. https://www.ncbi.nlm.nih.gov/pubmed/15461817
  20. Khan, Asaduzzaman MA (2013). "Hericium erinaceus: an edible mushroom with medicinal values". Journal of complementary & integrative medicine. 10 (1): 253–258. doi:10.1515/jcim-2013-0001. PMID 23735479.
  21. https://www.verywell.com/the-benefits-of-lions-mane-89474
  22. https://nihseniorhealth.gov/falls/causesandriskfactors/01.html